Morphology of Posterior Parietal Cortex Neurons using Go DISCO staining

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dc.contributor.advisorCelikel, Tansu
dc.contributor.authorFlipsen, Thomas Sebastiaan
dc.date.issued2019-07-01
dc.description.abstractThe posterior parietal cortex (PPC) is a highly connected brain region in the neocortex. Although it is critically involved in memory, navigation, and generation of an egocentric frame of reference, its cellular organization is yet to be studied in detail. Here, by employing a newly developed high-throughput staining method called goDISCO, we systematically study the morphological qualities of the PPC dendritic projections. We determined quantitative measures of pyramidal dendritic tree morphology under two ammonium concentrations and saw a significant decrease in staining quality for the lower ammonium concentration. Thus, a reduction in ammonium concentrations is not a viable means of reducing background noise in the goDISCO protocol.en_US
dc.embargo.lift2044-07-01
dc.embargo.typeTijdelijk embargoen_US
dc.identifier.urihttps://theses.ubn.ru.nl/handle/123456789/10834
dc.language.isoenen_US
dc.thesis.facultyFaculteit der Sociale Wetenschappenen_US
dc.thesis.specialisationResearchmaster Cognitive Neuroscienceen_US
dc.thesis.studyprogrammeResearchmaster Cognitive Neuroscienceen_US
dc.thesis.typeResearchmasteren_US
dc.titleMorphology of Posterior Parietal Cortex Neurons using Go DISCO stainingen_US
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