Frontal Alpha Asymmetry during Sleep in Depression
| dc.contributor.advisor | Dresler, M. | |
| dc.contributor.author | Varatheeswaran, Rathiga | |
| dc.date.issued | 2018-09-01 | |
| dc.description.abstract | This study was conducted to examine the presence of frontal alpha asymmetry during sleep among major depression patients and healthy controls, which is related to the di erence in lateralization of alpha power. The objective was to relate frontal alpha asymmetry during sleep to resting state encephalogram studies, where the asymmetry has been suggested to be a biomarker for depression. It was hypothesized that the patient group will show altered sleep patterns in comparison to healthy controls. Furthermore, the alpha power was expected to be increased in the left hemisphere in MDD patients. Moreover, it was expected that female responders to anti-depressants would show increased right-sided alpha power. The hypotheses were partially supported. There was no major di erence in asymmetry among MDD patients and control group. As expected, female responders did show increased right-sided alpha power, but only in sleep stage 1. Furthermore, male responders showed the same pattern but for sleep stage 2 and sleep stage 3. This study was one of the few studies relating the asymmetry to sleep. The results found here contribute to the understanding of the asymmetry during sleep and showed possible connections to resting state asymmetry research. Further investigation is needed to conclude whether the found di erences between female and male responders and non-responders across the sleep stages are meaningful and may re ect sleep- and MDD-related processes, such as emotional processing or executive control. | en_US |
| dc.embargo.lift | 2043-09-01 | |
| dc.embargo.type | Tijdelijk embargo | en_US |
| dc.identifier.uri | https://theses.ubn.ru.nl/handle/123456789/10117 | |
| dc.language.iso | en | en_US |
| dc.thesis.faculty | Faculteit der Sociale Wetenschappen | en_US |
| dc.thesis.specialisation | Researchmaster Cognitive Neuroscience | en_US |
| dc.thesis.studyprogramme | Researchmaster Cognitive Neuroscience | en_US |
| dc.thesis.type | Researchmaster | en_US |
| dc.title | Frontal Alpha Asymmetry during Sleep in Depression | en_US |