Altering functional connectivity in the brain by learning new associations

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2022-07-04

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en

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Synesthesia is a phenomenon in which sensory or cognitive stimuli can lead to additional involuntary experiences in a second sensory or cognitive pathway. The most common form of synesthesia is grapheme-color synesthesia. In grapheme-color synesthesia, viewing letters (graphemes) will elicit a perception of color. In previous research, it is shown that synesthesia-like experiences can be perceived by adults, who do not have synesthesia, by training specific letter-color associations. This thesis builds upon this by examining whether the training of these letter-color associations has altered the functional connectivity between regions of interest in the brain. Changes in functional connectivity between regions of interest when a specific sort of stimuli is presented are compared between pre-and post-training sessions and between conditions of interest. As a result of training these letter-color associations, increases and decreases in functional connectivity can be observed between regions of interest across the brain. We show that the functional connectivity in the brain is altered, although not always in the direction that we expect.

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Faculteit der Sociale Wetenschappen