Using semantic and graph similarity methods to predict heart or kidney abnormalities

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2022-01-30

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en

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There are many symptoms, which cannot be visually spotted. Imaging is needed to spot these symptoms, which is time intensive. Two examples of these symptoms are heart abnormalities and kidney abnormalities. These can be predicted with the use of graph and semantic similarity methods. Patients are represented as HPO graphs with symptoms being HPO nodes in the graph. Graph and semantic similarity can be used to compare patients with each other in order to make a classification based on the most similar patients. Resnik and Lin, two semantic similarity methods, have been compared to the maximum common sub-graph method, which is a graph similarity method. Overall the maximum common sub-graph method yields the best performance and has an AUC of 0.89. This can already be used with this data to determine the priority of the order in which patients undergo imaging.

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Faculteit der Sociale Wetenschappen