Power and object information in local field potentials in the rat perirhinal and prefrontal areas

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Local field potentials (LFPs) are the low-pass filtered portion of the extracellular electrical recordings reflecting the sub-threshold activity within a small radius around the cells. The goal of this study was to explore the electrophysiological signatures of the LFPs in the perirhinal cortex (PrH) and medial prefrontal cortex (mPFC) during object perception and object exploration in rats, as well as to quantify the information content regarding the identity of the perceived/explored objects in the activity of those regions. One adult Lister Hooded rat was implanted with two silicon probes (one in each area) and underwent a maze navigation task where during every trial different objects were placed in the two compartments of a bow-tie maze, such that the rat could freely explore them at any point of a trial. We found differential changes in the power in certain frequency bands of the brain regions in question in response to object perception or exploration (compared to a baseline of resting-state recording). Furthermore, we found non-zero mutual information coefficients for most region-frequency pairs, indicating that the instantaneous power in the activity of the brain areas in question did contain some information about objects. These results and their implications are discussed.
Faculteit der Sociale Wetenschappen