Between-subject variance in resting-state fMRI connectivity predicts fMRI activation in a language task

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dc.contributor.advisorFonteijn, Hubert
dc.contributor.advisorWillems, Roel
dc.contributor.authorZaadnoordijk, Lorijn
dc.date.issued2014-08-11
dc.description.abstractThe spatial response observed during fMRI experiments is generally highly variable across subjects. In the current study, we disentangled the inter-subject variance that reflects differences in the network topology of the brain and the variance caused by other effects (e.g. task compliance or engagement). Using resting-state connectivity and task-based activation during a language task, we found signif­icant correlations between variance across the two measures. The strength with which a region is connected to the language network during rest is found to be predictive of how active it is during language processing. This finding demonstrates that a significant portion of the inter-subject vari­ability observed in fMRI studies can be related to inter-individual differences in brain organization.en_US
dc.embargo.lift2042-08-11
dc.embargo.typeTijdelijk embargoen_US
dc.identifier.urihttps://theses.ubn.ru.nl/handle/123456789/7377
dc.language.isoenen_US
dc.thesis.facultyFaculteit der Sociale Wetenschappenen_US
dc.thesis.specialisationResearchmaster Cognitive Neuroscienceen_US
dc.thesis.studyprogrammeResearchmaster Cognitive Neuroscienceen_US
dc.thesis.typeResearchmasteren_US
dc.titleBetween-subject variance in resting-state fMRI connectivity predicts fMRI activation in a language tasken_US
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