Cortical Dynamics Consensus set approximation

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2021-07-01

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en

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Consensus set approximation refers to a technique that can be used to solve a Dual estimation problem, a problem in which one wishes to know both the signal in a dataset and the parameters for a model. Solving such problems for neurological systems can provide a low cost method for retrieving the state of e.g. the cortex in the brain. Previous work made it possible to use this method to approximate networks using this technique. In this research this method is expanded to solve this problem with the added constraint of attempting to discover regions with an anatomical basis. This is done by using such an approximation applied to an Unscented Kalman Filter with a Wilson-Cowan model in combination with A nity Propagation clustering. Two model variations were tested on several datasets containing voltage traces of ve mice across their dorsal cortices. Results show that not all data can be signi cantly approximated, however networks similar to other studies can be found. Future research could improve the numerical stability of the current method and optimize both noise and transition models in order to improve current results. Keywords: Kalman Filter, Unscented Kalman Filter, Wilson-Cowan Model, Consensus set, Data Assimilation, Dual Estimation

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Faculteit der Sociale Wetenschappen