Manipulating multisensory integration for reach planning using tendon vibration

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2020-03-10

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en

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To plan a movement, integration of di erent sensory inputs is necessary to form an estimate of the current state of the body relative to the environment. Reaching movements with the hand are a very common and essential part of human interaction with the environment. Motor planning for these reaching movements relies on input from visual and proprioceptive senses. These di erent senses can be integrated to obtain an informative estimate of hand position in order to be able to plan a goal-directed reach. At subsequent stages of planning the two senses need to be integrated with di erent relative weightings allowing for optimal integration of the two estimates. The integration weighting is dependent on the respective properties of the di erent motor planning stages. Here, we aim to study this integration process by manipulating the proprioceptive estimate of hand position. As the estimate of hand position can be described as a likelihood distribution around a location, we were interested in studying both manipulation of the precision and accuracy of this estimate. For the former, we developed a simultaneous agonist-antagonist vibration paradigm to test whether this can decrease precision of proprioceptive input after vibration cedes, with the muscle spindles adapting to the varying e ect of vibration. We tested 6 healthy adults on their accuracy and precision in a hand positioning task during agonist-antagonist vibration. They were tested in a baseline setup without vibration, then in 4 alternate blocks of applying 100 Hz vibration or no vibration during task performance. We analysed precision of nal position estimates, but also accuracy. The results suggest that precision is not decreased, and therefore that agonist-antagonist vibration does not decrease the quality of the proprioceptive input in this paradigm. Previous research indicates that unilateral tendon vibration induces an illusory displacement of the respective joint. In a second experiment, we used this knowledge to manipulate accuracy of the proprioceptive estimate of the hand to study the role of proprioception in multisensory integration for motor planning in a reaching task, using tendon vibration either on the biceps brachii or the triceps brachii. We tested 20 healthy adults in this paradigm. Participants had to reach from a central start position through eight circularly arranged target positions in the horizontal plane. Biceps, triceps and no-vibration trials were pseudorandomly interleaved. We analysed tangential reach direction at movement initiation (40% of maximum velocity). For most target directions there was a signi cant e ect of biceps and triceps vibration on the initial error in reach direction relative to no-vibration trials. These results support the important role of proprioception in estimating hand position and planning hand movements, where proprioception plays an especially large role when transforming planned movement vectors into executable motor commands.

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Faculteit der Sociale Wetenschappen